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ePub Molecular and Cellular Mechanisms of Neuronal Plasticity: Basic and Clinical Implications (Advances in Experimental Medicine and Biology) download

by Yigal H. Ehrlich

ePub Molecular and Cellular Mechanisms of Neuronal Plasticity: Basic and Clinical Implications (Advances in Experimental Medicine and Biology) download
Author:
Yigal H. Ehrlich
ISBN13:
978-0306460401
ISBN:
0306460408
Language:
Publisher:
Springer; 1998 edition (March 31, 1999)
Category:
Subcategory:
Medicine
ePub file:
1870 kb
Fb2 file:
1634 kb
Other formats:
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Rating:
4.8
Votes:
184

Advances in Experimental Medicine and Biology. Bioactive Lipids and Gene Expression in Neuronal Plasticity.

Advances in Experimental Medicine and Biology. The mechanisms underlying this neuronal plasticity are activated by experiential inputs and operate in the process of learning and the formation of memories in the brain. In addition to studies on the involement of functional proteins in neuronal adaptation, this volume presents recent developments on the critical roles of bioactive lipids and nucleotides in these processes.

of Neuronal Plasticity: Basic and Clinical Implications (Advances in Experimental Medicine and Biology)

Molecular and Cellular Mechanisms of Neuronal Plasticity: Basic and Clinical Implications (Advances in Experimental Medicine and Biology). Numerous studies have proven the biological basis of memory formation and have begun to identify the biochemical traces and cellular circuits that are formed by experience, and which participate int the storage of information in the brain, its retention for long durations, and its retrieval upon demand.

Basic and Clinical Implications. Books related to Molecular and Cellular Mechanisms of Neuronal Plasticity. by. series Advances in Experimental Medicine and Biology Books related to Molecular and Cellular Mechanisms of Neuronal Plasticity.

Neuronal and Vascular Plasticity: Elucidating Basic Cellular Mechanisms for Future Therapeutic Discovery addresses novel repair mechanisms for cellular injury and integrates current knowledge of basic disease mechanisms of the brain with clinical approaches

Neuronal and Vascular Plasticity: Elucidating Basic Cellular Mechanisms for Future Therapeutic Discovery addresses novel repair mechanisms for cellular injury and integrates current knowledge of basic disease mechanisms of the brain with clinical approaches. This volume is intended to serve as a strong reference for those entering the clinical neurosciences as well as for those established in the field.

Electronic address: absarmento. 5. Center for Neuroscience and Cell Biology and Institute for Biomedical Imaging and Life Sciences (CN. BILI), Coimbra, Portugal; Faculty of Pharmacy, University of Coimbra (FFUC); Coimbra, Portugal.

The book willserve as a reference for both basic neuroscientists and clinicians interested in an authoritative update on the molecular and cellular biology of neuroprotection and its promises for new therapeutic strategies. См. также: Неврология.

Therefore, understanding the molecular mechanisms of invasion and .

Therefore, understanding the molecular mechanisms of invasion and metastasis that take place in malignant cells will provide insight into the development of new therapeutic approaches. However, the complex processes of tumor invasion and metastasis pose a great difficulty in studying their molecular bases. Advances in the enrichment and analysis of rare cells from the bloodstream have allowed for detection and characterization of circulating tumor cells (CTCs) from patients with cancer.

This volume explores microRNA pathophysiology, focusing on basic concepts in molecular and cellular biology. microRNA: Basic Science is an ideal companion to both microRNA: Medical Evidence and microRNA: Cancer. Chapters contributed by leading scientists examine recently discovered pathways in several processes, including aging, diabetes, cardiovascular disease, hematopoiesis, and mitochondrial fitness.

The objective of the Pathology and Experimental Medicine collaborative program is to provide graduate students with the knowledge and skills to examine the basic mechanisms of disease pathology, and to develop new strategies for prevention and treatment. The degree awarded specifies the primary program and indicates Specialization in Pathology and Experimental Medicine.

The book will serve as a reference for both basic neuroscientists and clinicians interested in an authoritative update on the molecular and cellular biology of neuroprotection and its promises for new therapeutic strategies. Given the very limited capacity of regeneration in the brain, protecting neurons that are on the brink of death is a major challenge for basic and clinical neuroscience, with implications for a broad spectrum of acute and chronic neurological and psychiatric diseases.

Numerous studies have proven the biological basis of memory formation and have begun to identify the biochemical traces and cellular circuits that are formed by experience, and which participate int the storage of information in the brain, its retention for long durations, and its retrieval upon demand. Cells in the nervous system have the capability of undergoing extremely long-lasting alterations in response to hormonal, pharmacological, and environmental stimulations. The mechanisms underlying this neuronal plasticity are activated by experiential inputs and operate in the process of learning and the formation of memories in the brain. This volume presents research areas which have not been highlighted in the past. In addition to studies on the involement of functional proteins in neuronal adaptation, this volume presents recent developments on the critical roles of bioactive lipids and nucleotides in these processes. In addition to the widely studied role of second messengers, a review of studies on extracellular phosphorylation systems operating on the surface of brain neurons is presented.The first section of the volume presents studies of basic mechanisms operating in a wide range of adaptive processes. The second section presents recent advances in investigations that have demonstrated the clinical implications of this research. These include: state of the art use of transgenic models in studies of molecular and cellular mechanisms implicated in familial Alzheimer's disease and Amyotrophic Lateral Sclerosis; studies of specific proteins implicated in Alzheimer's disease, including an adapter that binds to the beta-amyloid precurser protein (beta-APP) and the microtubular protein Tau and its membrane-bound counterpart. The advantages of using cell culture models for elucidating the causes of neuronal degeneration and for identifying mechanisms of neuroprotection are also presented among the chapters in the section on clinical implications.