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ePub Integrated Strategies for Drug Discovery Using Mass Spectrometry (Wiley Series on Pharmaceutical Science and Biotechnology: Practices, Applications and Methods) download

by Mike S. Lee

ePub Integrated Strategies for Drug Discovery Using Mass Spectrometry (Wiley Series on Pharmaceutical Science and Biotechnology: Practices, Applications and Methods) download
Author:
Mike S. Lee
ISBN13:
978-0471461272
ISBN:
047146127X
Language:
Publisher:
Wiley-Interscience; 1 edition (June 29, 2005)
Category:
Subcategory:
Medicine
ePub file:
1189 kb
Fb2 file:
1549 kb
Other formats:
mobi txt mbr rtf
Rating:
4.8
Votes:
163

THIS BOOK: Clearly explains how drug discovery and mass .

Similar books to Integrated Strategies for Drug Discovery Using Mass . Journal of the American Society of Mass Spectrometry, March 2006).

with the purchase of any eligible product. As traditional methods of analysis become antiquated, new analytical strategies and techniques are necessary to meet sample throughput requirements and manpower constraints. Among them, mass spectrometry has grown to be a front-line tool throughout drug discovery.

Integrated Strategies for Drug Discovery Using Mass Spectrometry Wiley Series on Pharmaceutical Sci. KayEMcWhorter KayEMcWhorter.

As traditional methods of analysis become antiquated, new analytical strategies . THIS BOOK: Clearly explains how drug discovery and mass spectrometry ar. .

As traditional methods of analysis become antiquated, new analytical strategies and techniques are necessary to meet sample throughput requirements and manpower constraints.

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Mike S. Lee, Integrated Strategies for Drug Discovery Using Mass Spectrometry. Birendra Pramanik, Mike S. Lee, and Guodong Chen, Characterization of Impurities and Degradants Using Mass Spectrometry. Mike S. Lee and Mingshe Zhu, Mass Spectrometry in Drug Metabolism and Disposition: Basic Principles and Applications. Mass spectrometry handbook.

Current drug discovery involves a highly iterative process pertaining to three core disciplines: biology .

Current drug discovery involves a highly iterative process pertaining to three core disciplines: biology, chemistry, and drug disposition. For most pharmaceutical companies the path to a drug candidate comprises similar stages: target identification, biological screening, lead generation, lead optimization, and candidate selection.

Title: Integrated Strategies For Drug Discovery Using Mass Spectrometry. Publisher: Wiley-Interscience. Series: Wiley Series on Pharmaceutical Science and Biotechnology: Practices, Applications and Methods. Year: published in 2005.

Authors and affiliations.

New strategies and techniques for today's fast-paced discoveryprocessToday, the pressure is on for high-throughput approaches toaccelerate the generation, identification, and optimization ofmolecules with desirable drug properties. As traditional methods ofanalysis become antiquated, new analytical strategies andtechniques are necessary to meet sample throughput requirements andmanpower constraints. Among them, mass spectrometry has grown to bea front-line tool throughout drug discovery.Integrated Strategies for Drug Discovery Using Mass Spectrometryprovides a thorough review of current analytical approaches,industry practices, and strategies in drug discovery. The topicsrepresent current industry benchmarks in specific drug discoveryactivities that deal with proteomics, biomarker discovery,metabonomic approaches for toxicity screening, lead identification,compound libraries, quantitative bioanalytical support,biotransformation, reactive metabolite characterization, leadoptimization, pharmaceutical property profiling, sample preparationstrategies, and automation.THIS BOOK:* Clearly explains how drug discovery and mass spectrometry areinterconnected* Discusses the uses and limitations of various types of massspectrometry in various aspects of drug discovery* Prominently features analytical applications that requiretrace-mixture analysis* Provides industry applications and real-world examples* Shares historical background information on various techniques toaid in the understanding of how and why new methods are now beingemployed to analyze samples