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ePub Disease Gene Identification: Methods and Protocols (Methods in Molecular Biology) download

by Johanna K. DiStefano

ePub Disease Gene Identification: Methods and Protocols (Methods in Molecular Biology) download
Author:
Johanna K. DiStefano
ISBN13:
978-1617379536
ISBN:
1617379530
Language:
Publisher:
Humana Press; 2011 edition (January 10, 2011)
Category:
Subcategory:
Medicine
ePub file:
1704 kb
Fb2 file:
1304 kb
Other formats:
rtf docx mobi doc
Rating:
4.6
Votes:
129

Methods and Protocols .

Methods and Protocols. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

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Disease Gene Identification book. Start by marking Disease Gene Identification: Methods And Protocols (Methods In Molecular Biology) as Want to Read: Want to Read savin. ant to Read. This book details molecular methodologies used in identifying.

Disease Gene Identification. Johanna Kay DiStefano. Methods in Molecular Biology. Part I: Introduction 1. Technological Issues and Experimental Design of Gene Association Studies Johanna K. DiStefano and Darin . More). The development of next generation sequencing (NGS) technologies has transformed the study of human genetic variation.

3. 4. DiStefano and Taverna. Although there are millions of SNPs in the human genome, it is well recognized that the effect of an ungenotyped functional allele may still be gauged if it is correlated with a variant that has been genotyped.

Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known.

Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Download from free file storage.

Recent efforts to characterize genetic variation in the human genome, coupled with the rapidly developing field of genomics, have lead directly to the development of new and innovative approaches to the identification of genes contributing to complex human diseases. In Disease Gene Identification: Methods and Protocols, expert researchers in the field provide up-to-date molecular methodologies used in the process of identifying a disease gene, from the initial stage of study design to the next stage of preliminary locus identification, and ending with stages involved in target characterization and validation. As a volume in the highly successful Methods in Molecular Biology™ series, chapters contain brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and detailed tips on troubleshooting and avoiding known pitfalls. Authoritative and essential, Disease Gene Identification: Methods and Protocols seeks to aid scientists striving toward the identification and characterization of the many disease-related genes, which may someday pave the way for more accurate and improved methods of disease diagnosis as well as vital strategies for disease treatment and prevention.