candidate for sustained release formulation. Key Words: Diclofenac sodium, pectin, sustained release matrix tablets. release of Diclofenac sodium from pectin based

candidate for sustained release formulation. release of Diclofenac sodium from pectin based. matrix was showed in Figure 4. MALVIYA RISHABHA et al: FORMULATION AND OPTIMIZATION OF SUSTAINED RELEASE. Drug Dev. & Re. April-June 2010, 2(1):330-335.

Among different formulations, F1 showed sustained release of drug for 12 hours with 8. 7% release. The effect of other parameters like addition of release modifier (PEG 6000), gum concentration, pH of dissolution medium, rotation speed and dissolution by paddle method, were also studied. Selected formulation (F1) was subjected to stability studies for three months at 0-4°, room temperature (28°), and 45° with RH 75±5%, and showed stability with respect to release pattern. Table 2: Physical Properties Of Diclofenac Sodium Sr Matrix Tablets. All formulations showed very low drug release in . N HCl (pH . )

Among different formulations, F1 showed sustained release of drug for 12 hours with 8. ). This was due to the very low solubility of diclofenac sodium at pH . Sustained, but complete drug release was displayed by all formulations in phosphate buffer (pH .

Matrix Based Sustained Release Formulations of Diclofenac sodium. The aim of this book was to provide basic knowledge of the art for the development of controlled release matrix tablets of diclofenac sodium with synthetic (Hydroxypropyl Methyl Cellulose) and natural (Xanthine Gum) hydrophilic polymers using different concentrations by direct compression technique and to comparatively evaluate the formulations on the basis of in-vitro and in-vivo parameters. An in-vivo study was conducted on rabbits and the results were calculated using different software like SPSS and Kinetica.

Sustained release tablets of Diclofenac Sodium were fabricated using Cashew nut tree gum, HPMC and Carbopol. The tablets were evaluated for preformulation studies like angle of repose, bluk density, compressibility index and physical characteristics like hardness, weight variation, fraibilty and drug content. In-vitro release of drug was performed in PBS pH . for twelve hours. All the physical characters of the fabricated tablet were within acceptablelimits

Sustained Release Tablets: Matrix Based Sustained Release Formulations of Diclofenac sodium. by Ghulam Murtaza, M. S. H. Akash, S. N. Shah.

Sustained Release Tablets: Matrix Based Sustained Release Formulations of Diclofenac sodium. ISBN 9783843385244 (978-3-8433-8524-4) Softcover, LAP LAMBERT Academic Publishing, 2010. Founded in 1997, BookFinder. com has become a leading book price comparison site

Sustained Release Tablets: Matrix Based Sustained Release Formulations of. .Development of Controlled Release Three-layered Diclofenac Tablet

Sustained Release Tablets: Matrix Based Sustained Release Formulations of Diclofenac sodium. Then you can start reading Kindle books on your smartphone, tablet, or computer - no Kindle device required.

The effects of formulation variables on the release profile of diclofenac sodium (DS) from hydroxypropylmethyl cellulose (HPMC) and chitosan matrix tablets were studied

The effects of formulation variables on the release profile of diclofenac sodium (DS) from hydroxypropylmethyl cellulose (HPMC) and chitosan matrix tablets were studied. DS tablets were prepared by wet granulation and direct compression methods and different ratios of HPMC and chitosan were used. Physical properties of the prepared tablets and targeted commercial sustained release (SR) tablet and the drug release were studied in tablets that were placed in . M HCl for 1 h and phosphate buffer solution was added to reach pH value of . Design and evaluation of Xanthan gum-based sustained release Matrix tablets of Diclofenac sodium. oceedings{Yeole2006DesignAE, title {Design and evaluation of Xanthan gum-based sustained release Matrix tablets of Diclofenac sodium}, author {P. G. Yeole and Upendra Chandrakant Galgatte and Ib Babla and Pd Nakhat}, year {2006} }.