Each timely volume contains a wealth of information on the featured subject

Each timely volume contains a wealth of information on the featured subject.

DNA Methylation: Development, Genetic Disease and Cancer . The chapters in the book describe an increasingly complex set of interactions that are beginning to be unraveled between the autophagy pathway, infectious dis-eases, and immunity. In its most primal form, autophagy may be a universal defense mechanism by which individual eukaryotic cells (or unicellular organisms) protect themselves in a cell-autonomous fashion by eating the microbes that attack them. Hopefully, this volume of Current Topics in Microbiology and Immunology will stimulate investi-gators to delve even deeper into this exciting field.

The structural and functional importance of the correct patterns of DNA methylation in all parts of a mammalian genome is, unfortunately, not well understood

The structural and functional importance of the correct patterns of DNA methylation in all parts of a mammalian genome is, unfortunately, not well understood. The stability, inheritability, and developmental flexibility of these patterns all point to a major role that these patterns appear to play in determining structure and funtion of the genome. Up to the present time, studies on the repetitive sequences, which comprise more than 90 per cent of the DNA sequences in the human or other genomes, have been neglected.

Read instantly in your browser. Series: Current Topics in Microbiology and Immunology (Book 310). Hardcover: 284 pages.

Peter A. Jones, Peter K. Vogt. This book is a comprehensive survey of new and exciting developments regarding the role of DNA methylation in human cancer. Issues related to the mutagenicity of 5-methylcytosine and the increase in the interaction of chemical and physical carcinogens with these residues is discussed. The book summarizes the modulation of viral gene expression and the silencing of tumor suppressor genes and illustrates mechanisms by which the methylation signal is translated into altered chromatin structure.

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Goodreads helps you keep track of books you want to read. Start by marking Current Topics in Microbiology and Immunology, Volume 310: DNA Methylation: Development, Genetic Disease and Cancer as Want to Read: Want to Read savin. ant to Read. Thus, it is not surprising that studies on the role of DNA methylation now occupy center stage in many It has become apparent that the genomes of many organisms are characterized by unique patterns of DNA methylation which can differ from genome segment to genome segment and cell type to cell type. These patterns can be instrumental in determining cell type and function.

DNA methylation in cancer plays a variety of roles, helping to change the healthy regulation of gene expression to a disease pattern. However, during development and formation of different tissues epigenetic factors change

DNA Methylation: Development, Genetic Disease and Cancer (Current Topics in Microbiology and Immunology). ISBN 13: 9783642068300. DNA Methylation: Development, Genetic Disease and Cancer (Current Topics in Microbiology and Immunology).

Cancer and Autoimmunity (Current Topics in Microbiology and Immunology).

The structural and functional importance of the correct patterns of DNA methylation in all parts of a mammalian genome is, unfortunately, not well understood. The stability, inheritability, and developmental flexibility of these patterns all point to a major role that these patterns appear to play in determining structure and function of the genome.

Each timely volume contains a wealth of information on the featured subject.