ePub Phencyclidine and Related Arylcyclohexylamines: Present and Future Applications download
by Jean-Marc Kamenka,E. F. Domino,Patrick Geneste
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In Phencyclidine and Related : Present and Future Applications, ed. by . Domino, and P. Geneste, pp 59–69, NPP press, Ann Arbor. Demonstration of cyclazocine binding to multiple opiate receptor sites. Cite this chapter as: Hoffer . Palmer . Moore . Kim . Wang Y. (1987) The Relationships of Receptors for Phencyclidine and Sigma Opiates in Rat Cerebellum: An Analysis. In: Fuxe . Agnati . eds) Receptor-Receptor Interactions. Wenner-Gren Center International Symposium Series. Springer, Boston, MA.
Phencyclidine, the prototypal arylcyclohexylamine derivative. PCE was reported in 1953 and PCMo in 1954, with the latter compound described as a potent sedative. Arylcyclohexylamine anesthetics were intensively investigated at Parke-Davis, beginning with the 1956 synthesis of phencyclidine and later the related compound ketamine. The 1970s saw the debut of these compounds, especially PCP and its analogues, as illicitly used recreational drugs due to their.
S. n. ung. The preferential conformations of phencyclidine and cyclohexyl substituted derivatives were determined by NMR and pKa measurements. Methoxetamine (MXE) is increasingly used and abused, as it is frequently presented as being safer than ketamine, and legal. Cases of only MXE consumption being associated with the occurrence of seizures are rarely reported.
This study tested structural analogs of phencyclidine (PCP) using drug discrimination procedures to. .In: Kamenka JM, Domino EF, Geneste P (eds) Phencyclidine and related : present and future applications. NPP Books, Ann Arbor, Michigan, 1983.
This study tested structural analogs of phencyclidine (PCP) using drug discrimination procedures to determine which analogs produced discriminable effects similar to those of PCP. It also tested the utility of multiple-drug discrimination training (PCP versus other drugs or saline) as a method for increasing the specificity produced by training. All discrimination training took place in two-lever operant compartments using FR-10 reinforcement of presses on the correct lever.
D Phencyclidine and Related : Present and Future Applications; Kamenka, J. Domino,E.
Cantrell, B. Leander, J. Mendelsohn, L. Schoepp, D. Hermann, R. Zimmerman, D. M. In Sigma and Phencyclidine-Like Compounds as Molecular Probes in Bi-ology;Domino, E. Kamenka, J. Ed. NPP Books: Ann Arbor, MI, 1988; pp 11-17. Woods, J. Hynes, M. Cantrell, B. Reamer, . D. In Phencyclidine and Related : Present and Future Applications; Kamenka, J. Geneste, . NPP Books: Ann Arbor, MI, 1983; pp 59-69. Nakajima, S. J. Pharm.
Kamenka JM, Domino EF: Phencyclidine and related
Kamenka JM, Domino EF: Phencyclidine and related. Ann Arbor, NPP Books, 1983 24. Kamenka JM, Domino EF: Multiple Sigma and PCP Receptor Ligands: Mechanisms for Neuromodulation and Neuroprotection. Ann Arbor, NPP Books, 1992 25. Domino EF, Kamenka JM: Sigma and Phencyclidine-Like Compounds as Molecular Probes in Biology. Ann Arbor, NPP Books, 1988 26. Lodge D, Ands NA, Berry SC, Burton NR: selectively reduce excitation of mammalian neuroncs by aspartate-like amino acids. In: Phencyclidine and Related (Kamenka JM, Domino EF, Geneste.
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